International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 6 Issue 6 November-December 2024 Submit your research before last 3 days of December to publish your research paper in the issue of November-December.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 6 Issue 6
November-December 2024

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

Formulation and Evaluation of Mouth Dissolving Loratadine Tablet using Super Disintigrants

Author(s) S.Kavya, S.Sangeetha, S.Chandra, N.Senthil Kumar
Country India
Abstract The objective of the work was design to improve palatability in orally administered products has prompted the development of formulation with improved performance and acceptability. Mouth-dispersing tablets dissolve or break down in saliva and are ingested without the use of water. Antihistamine loratadine is primarily used to treat hay fever, allergies, itchy eyes, and hives symptoms. It functions by obstructing histamine, which the body releases after an allergic reaction. The objective of the current study was to use the physical mixing approach to increase the solubility and dissolving rate using Croscarmellose sodium. From FIIR identification of drug is done and followed by physicochemical parameters. Determination of drug polymer incompatibility is by FTIR method. Loratadine MDT were prepared by using different superdisintegrants as Croscarmellose sodium, Orange peel pectine and Hibiscus mucilage by direct compression method. Only the physiochemical characterization, formulation, and in-vitro assessment of Loratadine mouthwash pills were carried out in this study. In addition to in-vitro research, in-vivo drug studies are crucial . Future in-vivo research is vital to establish the in-vitro in-vivo correlation that is required for the development of successful formulations and also long term stability studies.
Keywords Loratadine, Super disintegrants, Croscarmellose sodium, Mouth soluble tablet, In-vitro drug release.
Field Medical / Pharmacy
Published In Volume 5, Issue 6, November-December 2023
Published On 2023-12-11
Cite This Formulation and Evaluation of Mouth Dissolving Loratadine Tablet using Super Disintigrants - S.Kavya, S.Sangeetha, S.Chandra, N.Senthil Kumar - IJFMR Volume 5, Issue 6, November-December 2023. DOI 10.36948/ijfmr.2023.v05i06.10349
DOI https://doi.org/10.36948/ijfmr.2023.v05i06.10349
Short DOI https://doi.org/gs8397
View / Download PDF File

Share this



E-ISSN 2582-2160
CrossRef

CrossRef DOI is assigned to each research paper published in our journal.

IJFMR DOI prefix is
10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form Cover Page Vol 6 Isu 6Cover Page Vol 6 Isu 5Cover Page Vol 6 Isu 4

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9898-5948-55 editor@ijfmr.com