Incidence and Management of Fungal Infections in Oral and Maxillofacial Surgery

Author(s)	ROHIT NARENDRA RTHOD
Country	India
Abstract	Mucormycosis are life-threatening fungal infections especially affecting immunocompromised or diabetic patients. This review provides an update on mucormycosis management. The latest recommendations strongly recommend as first-line therapy the use of liposomal amphotericin B (≥ 5mg/kg) combined with surgery whenever possible. Isavuconazole and intravenous or delayed-release tablet forms of posaconazole have remained second-line. Many molecules are currently in development to fight against invasive fungal diseases but few have demonstrated efficacy against Mucorales. Despite in vitro efficacy, combinations of treatment have failed to demonstrate superiority versus monotherapy. New approaches assessing relationships between host, fungi, and antifungal drugs, and new routes of administration such as aerosols could improve mucormycosis treatment.
Keywords	FUNGAL INFECTIONS , MANGEMENT , ORAL AND MAXILLOFACIAL SURGERY
Field	Medical / Pharmacy
Published In	Volume 5, Issue 6, November-December 2023
Published On	2023-12-20
Cite This	Incidence and Management of Fungal Infections in Oral and Maxillofacial Surgery - ROHIT NARENDRA RTHOD - IJFMR Volume 5, Issue 6, November-December 2023. DOI 10.36948/ijfmr.2023.v05i06.10422
DOI	https://doi.org/10.36948/ijfmr.2023.v05i06.10422
Short DOI	https://doi.org/gs98vw

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