International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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Screening of Bioactive Compounds from Madagascar Periwinkle and Their Importance in Drug Discovery

Author(s) Muthu Tanya, Dharitri Priyadarsini, Rajat Kumar Nayak
Country India
Abstract The phytochemicals present in medicinal plants are effective and safe alternative to the chemically synthesized drugs for various diseases. Madagascar periwinkle grown as ornamental plant for its flowers. It is an evergreen that was native to the Madagascar Island. It is so special due to the variety of bioactive compounds present which have medicinal values, including anti-inflammatory, anti-cancer and anti-diabetic quality. This study aims to investigate phytochemical analysis of crude aqueous, methanol, chloroform and acetone extracts from leaves and flower of C. roseus. Qualitative preliminary phytochemical analysis revealed that the presence of alkaloid, flavonoids, tannin, phenol, and carbohydrate in all extracts of C. roseus. Both the aqueous and acetone extract of leaf and flower lacks terpenoid, protein, and resin. The most important alkaloids vinblastine and vincristine are derived from leaves and they exhibits anti-cancer and anti-diabetic property. These findings imply that the plant still has the potential to be a valuable source of bioactive substances. Further pharmacological and toxicity studies are necessary to be explored which can be used for the development of medicines.
Keywords Phytochemicals, C. roseus, Alkaloid, Flavonoid, Tannin, Anti-Cancer, Anti-Diabetic
Published In Volume 4, Issue 6, November-December 2022
Published On 2022-11-23
DOI https://doi.org/10.36948/ijfmr.2022.v04i06.1065
Short DOI https://doi.org/grb59g
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E-ISSN 2582-2160
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