International Journal For Multidisciplinary Research

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Antihyperglycemic Effect of Aqueous Extract of Boscia Senegalensis in Rabbits

Author(s) OKONDZA NOHYA Delvina, SOUDY Imar Djibrine, Amine ALHADJ SOULEYMANE, PATCHA Madjimbaye, MAHAMAT DJIDDA Adoum, ABDELKARIM HAMIT Daoud, LENGA Arsène
Country Congo
Abstract Introduction
Diabetes is a serious chronic disease that occurs when the pancreas does not produce enough insulin or when the body does not properly use the insulin produced. A distinction is made between type 1 and type 2 diabetes, which increases the risk of death. This work aims to study the anti hyperglycemic effect of B. senegalensis used in Chad to fight type II diabetes and metabolic syndrome.
Methodology
The Oral Glucose Tolerance Test was carried out, causing hyperglycemia in rabbits, followed by the incorporation of aqueous extract of Boscia senegalensis in the treatment batch. Then, a toxicity study was carried out using a standard method.
Results
The results showed that in treated rabbits, the incorporation of aqueous extract of B. senegalensis after glucose administration, led to a drop in blood sugar (1.35mg/dl to 1.22 mg/dl). The increase in blood glucose in control rabbits (1.23 mg/dl to 1.38 mg/dl) due to glucose administration persisted. The ratio of organ weight and body weight of the two lots of rabbits showed no significant difference.
Conclusion
This study confirmed the safety of B. senegalensis extract and reduce significantly the rate of glucose in the blood fighting against type 2 diabetes.
Keywords hyperglycemia, Boscia senegalensis, toxicity
Published In Volume 6, Issue 1, January-February 2024
Published On 2024-01-06
Cite This Antihyperglycemic Effect of Aqueous Extract of Boscia Senegalensis in Rabbits - OKONDZA NOHYA Delvina, SOUDY Imar Djibrine, Amine ALHADJ SOULEYMANE, PATCHA Madjimbaye, MAHAMAT DJIDDA Adoum, ABDELKARIM HAMIT Daoud, LENGA Arsène - IJFMR Volume 6, Issue 1, January-February 2024. DOI 10.36948/ijfmr.2024.v06i01.11515
DOI https://doi.org/10.36948/ijfmr.2024.v06i01.11515
Short DOI https://doi.org/gtdsc2
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