Diabetes Insipidus can Increase Patient Security: A Review

Alka sen; Farhat khan; Chetna singh thakur

doi:10.36948/ijfmr.2024.v06i01.13532

Diabetes Insipidus can Increase Patient Security: A Review

Author(s)	Alka sen, Farhat khan, Chetna singh thakur
Country	India
Abstract	Diabetes insipidus (DI) is a condition marked by polydipsia (drinking more than three liters of fluid per day) and a high hypotonic urine production (greater than 50 milliliters per kilogram of body weight per 24 hours). The hypothalamus or pituitary gland's insufficient production of arginine vasopressin (AVP) and its consequent inadequate secretion cause central DI. In addition to central DI, different primary forms (of renal origin) or secondary forms of polyuria may be the cause of additional underlying etiologies of DI. These variations are all part of the Polyuria Polydipsia Syndrome. This is crucial since different treatment plans have different effects, and using the incorrect one can be harmful. Since its discovery in 1942, diabetes insipidus has been linked to pregnancy complications in at least 4 out of every 100,000 patients.The regulatory mechanisms behind CDI and NDI are then discussed, with an emphasis on the water channel molecule aquaporin 2 (AQP2) and the vasopressin receptor 2 (V2R) regulatory axis. (DI) is a complicated pregnancy condition that can affect about 1 in 30,000 pregnancies. It is a heterogeneous illness that most commonly manifests as polyuria and polydipsia. The pathophysiology of DI during pregnancy determines the course of treatment; DI without AVP can be managed with desmopressin (DDAVP); DI with AVP resistance necessitates investigation of the underlying reasons. Previously known as diabetes insipidus (DI), arginase vasopressin disorder is a disease condition that causes electrolyte imbalances by either reducing the secretion of antidiuretic hormone (ADH, also known as vasopressin or AVP) or by reducing the body's response to ADH. Both arginine vasopressin deficiency (AVP-D; formerly known as central DI) and arginine vasopressin resistance (AVP-R; formerly known as nephrogenic DI) are forms of arginine vasopressin disease, with both congenital and acquired origins. Lithium increased the amount of lipid peroxidation (LPO) and reactive oxygen species (ROS) in the kidney.
Keywords	diabetes insipidus,aquaporin,vasopressin,polydipsia.
Field	Medical / Pharmacy
Published In	Volume 6, Issue 1, January-February 2024
Published On	2024-02-19
Cite This	Diabetes Insipidus can Increase Patient Security: A Review - Alka sen, Farhat khan, Chetna singh thakur - IJFMR Volume 6, Issue 1, January-February 2024. DOI 10.36948/ijfmr.2024.v06i01.13532
DOI	https://doi.org/10.36948/ijfmr.2024.v06i01.13532
Short DOI	https://doi.org/gtjtz3

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Diabetes Insipidus can Increase Patient Security: A Review

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