International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 6 Issue 4 July-August 2024 Submit your research before last 3 days of August to publish your research paper in the issue of July-August.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 6 Issue 4
July-August 2024

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

In-Vitro and In-Silico Analysis of Antimicrobial Efficacy in Annona Muricata Leaf Extracts

Author(s) Shivali U Shetty, Sanjeev Rai B, Beena Antony, Animik Ray, Shruthi B, Sanjeev Rai B
Country India
Abstract Annona muricata and Annona reticulata, known for their traditional medicinal uses and antimicrobial properties, were investigated for their potential antibacterial effects. Extracts from fresh leaves were tested for antimicrobial activity, revealing that Annona muricata exhibited superior antibacterial properties compared to Annona reticulata, especially against E. coli strains. In silico analysis focused on 46 phytochemicals extracted from Annona muricata, which were docked with key bacterial proteins, including Gyrase, the 30S and 50S ribosomal subunits, Topoisomerase IV, and penicillin-binding protein. Notably, phytochemicals such as Quercetin 3–O-rutinoside (Rutin), Quercetin 3-O-neohesperidoside, Quercetin 3-O-glucoside (Isoquercetin), Luteolin 3´7-di-O-glucoside, and Homoorientin demonstrated strong docking scores and confidence score, indicating potential interactions that could lead to bacterial destruction. These findings suggest that certain phytochemicals of Annona muricata is a promising candidate for antibiotic development, opening avenues for further exploration in combating bacterial infections.
Keywords Antibacterial Effects, Phytochemicals, Anonna muricata, Molecular Docking
Field Biology
Published In Volume 6, Issue 1, January-February 2024
Published On 2024-02-18
Cite This In-Vitro and In-Silico Analysis of Antimicrobial Efficacy in Annona Muricata Leaf Extracts - Shivali U Shetty, Sanjeev Rai B, Beena Antony, Animik Ray, Shruthi B, Sanjeev Rai B - IJFMR Volume 6, Issue 1, January-February 2024. DOI 10.36948/ijfmr.2024.v06i01.13628
DOI https://doi.org/10.36948/ijfmr.2024.v06i01.13628
Short DOI https://doi.org/gtjtxx
View / Download PDF File

Share this


E-ISSN 2582-2160
CrossRef

CrossRef DOI is assigned to each research paper published in our journal.

IJFMR DOI prefix is
10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form Cover Page Vol 6 Isu 4 Cover Page Vol 6 Isu 3 Cover Page Vol 6 Isu 2

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9898-5948-55 editor@ijfmr.com