Risk Associated with Antibiotic in Irritable Bowel Syndrome (IBS), Role of Microbiota and Future Aspects

Tonushyam Sonowal; Chinmoyee Deori; Leena Hujuri; Daisy Narzari; Dr. Jesim Ali Ahmed

doi:10.36948/ijfmr.2024.v06i01.13916

Risk Associated with Antibiotic in Irritable Bowel Syndrome (IBS), Role of Microbiota and Future Aspects

Author(s)	Tonushyam Sonowal, Chinmoyee Deori, Leena Hujuri, Daisy Narzari, Dr. Jesim Ali Ahmed
Country	India
Abstract	Irritable bowel syndrome (IBS) is functional gastrointestinal (GI) disorder that characterized by abdominal pain in relation to disturbed bowel habits. It is a substantial burden on both patient health –related quality of life and healthcare cost. Although various path physiologic mechanisms have been formulated including visceral hypersensitivity, altered bowel motility, gut- brain dysregulations but it is believed that gut microbiome plays an important role in the genesis of symptoms. The composition and diversity of the gut micro biota can be modified by use of antibiotics, as they have the capacity to diminish the levels of advantageous bacteria while allowing the proliferation of detrimental bacteria. It is well known that micro biome takes a crucial role in development of IBS, but antibiotics itself is a potential risk factors for IBS has not been clarified yet. However, lack of highly predictive diagnostics biomarkers and the complexity and the heterogeneity of IBS patients make management difficult and unsatisfactory in most of the cases, thereby reducing patient health- related quality of life and increasing the sanitary burden. So, this review would help us to understand the risk factors associated with antibiotics in developing IBS, the role of gut micro biome and the other potential future approaches which are useful for the diagnosis, prevention and treatment of irritable bowel syndrome.
Keywords	Irritable bowel syndrome (IBS), Gut microbiota, Antibiotic risk
Field	Medical / Pharmacy
Published In	Volume 6, Issue 1, January-February 2024
Published On	2024-02-23
Cite This	Risk Associated with Antibiotic in Irritable Bowel Syndrome (IBS), Role of Microbiota and Future Aspects - Tonushyam Sonowal, Chinmoyee Deori, Leena Hujuri, Daisy Narzari, Dr. Jesim Ali Ahmed - IJFMR Volume 6, Issue 1, January-February 2024. DOI 10.36948/ijfmr.2024.v06i01.13916
DOI	https://doi.org/10.36948/ijfmr.2024.v06i01.13916
Short DOI	https://doi.org/gtjtts

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Risk Associated with Antibiotic in Irritable Bowel Syndrome (IBS), Role of Microbiota and Future Aspects

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