Nanostructured Lipid Carrier for Hyperpigmentation Treatment - a Dermal Prospective

Ajeth. G; E. Gopinath; Ganesh N S; Adlin Jino Nesalin; Vineeth Chandy

doi:10.36948/ijfmr.2024.v06i01.14029

Nanostructured Lipid Carrier for Hyperpigmentation Treatment - a Dermal Prospective

Author(s)	Ajeth. G, E. Gopinath, Ganesh N S, Adlin Jino Nesalin, Vineeth Chandy
Country	India
Abstract	The normal human skin is exposed to different types of infection like wrinkles, pigmentation, acne, pimples in which pigmentation is most common in women over 30-40 years. The field of nanotechnology is currently intensely exploited for drug delivery technology for passive and active targeting via various routes of administration, such things can be effectively treated by incorporating the drug, loaded in a Nanostructured lipid carrier (NLC). NLCs have shown potential in delivering poorly soluble active components and in depigmenting. NLC springs up as the second generation of lipid nanoparticles to overcome the shortcomings of first generation through the topical route. NLC in topical administration provides some added advantages like increasing skin hydration and modified release profile and increase in skin penetration leading to avoidance of systemic absorption. NLCs are composed of biocompatible lipids, surfactants, and cosurfactants which help enhance drug loading capacity and stabilize the formulation. NLC's remarkable physicochemical and subsequently biocompatible qualities have created an ongoing need for the development of beneficial and safe drug delivery methods. The key attributes of NLC that make them a promising drug delivery system are ease of preparation, biocompatibility, the feasibility of scale-up, non-toxicity, improved drug loading, and stability Their ingredients have a special impact on the end product's physicochemical characteristics and efficacy. The present review aims to focus on the recent advancement in the preparation, characterization, and applications of NLC in treating hyperpigmentation.
Keywords	Dermal, Carriers, Penetration, Stability
Field	Medical / Pharmacy
Published In	Volume 6, Issue 1, January-February 2024
Published On	2024-02-28
Cite This	Nanostructured Lipid Carrier for Hyperpigmentation Treatment - a Dermal Prospective - Ajeth. G, E. Gopinath, Ganesh N S, Adlin Jino Nesalin, Vineeth Chandy - IJFMR Volume 6, Issue 1, January-February 2024. DOI 10.36948/ijfmr.2024.v06i01.14029
DOI	https://doi.org/10.36948/ijfmr.2024.v06i01.14029
Short DOI	https://doi.org/gtkthc

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Nanostructured Lipid Carrier for Hyperpigmentation Treatment - a Dermal Prospective

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