International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 6 Issue 6 November-December 2024 Submit your research before last 3 days of December to publish your research paper in the issue of November-December.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 6 Issue 6
November-December 2024

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

Lipid Profile in Patients with and Without Acute Coronary Syndrome

Author(s) Rabin Rai, Sangeeta Naorem, Victoria Kshetrimayum, Sachin Deba, Bidya Nongmaithem, Guiphiuliu Kamei
Country India
Abstract Background: Coronary heart disease (CHD) remains the major cause of mortality and morbidity in the entire world population despite therapeutic advances that control many risk factors. Lipid profile is regarded as an important factor in the development of coronary heart disease. There have been numerous studies showing the association of hyperlipidemias with coronary heart disease in most of the Western as well as Asian countries of the world. But we have very little data on the relation between CHD and lipid profile in this part of the globe.
Objective: To evaluate the association between lipid profile and acute coronary syndrome (ACS).
Methods: This cross-sectional study was done in the Department of Biochemistry in collaboration with the Department of Cardiology, Regional Institute of Medical Sciences, Imphal on diagnosed cases of acute coronary syndrome in between January 2021 to October 2022. Estimation of lipid profile was done by Randox Imola autoanalyzer. Data collected were entered in SPSS version 21.0 and analysed using descriptive measures, and statistical significances were set at p<0.05.
Results: A total of 67 patients of acute coronary syndrome and 67 without acute coronary syndrome (total 134) were recruited in the study. It is seen that the mean±SD of age in cases was 63.69±12.11 years and in the controls, it was 45.47±11.75 years, and the difference observed was found to be statistically significant p<0.05. The majority of the cases were males comprising of 49 (73.3%) and females constitute only 18 (26.7%). 42 (62.2%) of the cases had history of HTN while 25 (37.8%) had no h/o HTN. In cases the mean±SD of SBP (112.67±17.35 mmHg) and DBP (73.38±11.63 mmHg) were found to be significantly lower than the controls. As regards the lipid profile, in the cases the mean±SD of total cholesterol was 208.75±31.25 mg/dl and in controls 144.02±19.57 mg/dl, triglycerides in cases was 162.51±39.81 mg/dl and 98.42±16.96 mg/dl in controls and LDL was 142.22±31.31 mg/dl in the cases and 71.40±21.24 mg/dl in controls showing that the values were higher in the cases as compared to the control group and the difference was found to be statistically significant with p<0.05. However, the mean±SD of HDL in the cases (34.78±6.44 mg/dl) was lower as compared to the controls (49.56±5.72 mg/dl) and the difference was statistically significant with p<0.05.
Conclusion: In this study, it was found that the total cholesterol, triglycerides, and LDL cholesterol concentrations were significantly higher and HDL concentration was lower in acute coronary syndrome (ACSD) patients. The imbalance between TC and HDL levels plays a more important role in the pathophysiology of atherogenesis leading to ACS.
Keywords ACS, lipid profile, blood pressure, dyslipidemia
Field Medical / Pharmacy
Published In Volume 5, Issue 1, January-February 2023
Published On 2023-01-20
Cite This Lipid Profile in Patients with and Without Acute Coronary Syndrome - Rabin Rai, Sangeeta Naorem, Victoria Kshetrimayum, Sachin Deba, Bidya Nongmaithem, Guiphiuliu Kamei - IJFMR Volume 5, Issue 1, January-February 2023. DOI 10.36948/ijfmr.2023.v05i01.1411
DOI https://doi.org/10.36948/ijfmr.2023.v05i01.1411
Short DOI https://doi.org/grpdp5
View / Download PDF File

Share this



E-ISSN 2582-2160
CrossRef

CrossRef DOI is assigned to each research paper published in our journal.

IJFMR DOI prefix is
10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form Cover Page Vol 6 Isu 6Cover Page Vol 6 Isu 5Cover Page Vol 6 Isu 4

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9898-5948-55 editor@ijfmr.com