Evaluation of Genotoxic Effect of Marigold (Tagetes Erecta) Leaf Extract in Mice on Mitotic Chromosome

Author(s)	Praveen Kumar Rana, Dharmshila Kumari
Country	India
Abstract	In this study, 10% Marigold leaf extract was tested for possible genotoxicity by looking at mitotic aberrations. The study aimed to determine potential variations in the incidence of mitotic chromosomal abnormalities by comparing two groups: one group was treated with 10% Marigold leaf extract, and the other group received no therapy. The control group had a total of 37% mitotic chromosomal abnormalities, which included 24% structural abnormalities and 13% disruptive abnormalities. Conversely, On the other hand, the treatment group (who received a 10% Marigold leaf extract) exhibited a total of 53.00% mitotic aberrations, of which 25.00% were structural and 28.00% were disruptive. Compared to the control group, this percentage of anomalies was substantially (P<0.01) higher.10% of marigold leaf extract may be genotoxic.
Keywords	Bone Marrow, Mitotic disruptive Abnormalities, Mitotic Structural Abnormalities, Tagetes erecta
Field	Biology > Zoology
Published In	Volume 6, Issue 2, March-April 2024
Published On	2024-04-01
Cite This	Evaluation of Genotoxic Effect of Marigold (Tagetes Erecta) Leaf Extract in Mice on Mitotic Chromosome - Praveen Kumar Rana, Dharmshila Kumari - IJFMR Volume 6, Issue 2, March-April 2024. DOI 10.36948/ijfmr.2024.v06i02.15962
DOI	https://doi.org/10.36948/ijfmr.2024.v06i02.15962
Short DOI	https://doi.org/gtpw83

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