International Journal For Multidisciplinary Research
E-ISSN: 2582-2160
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A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal
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Volume 6 Issue 6
November-December 2024
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Detection of Methicillin Resistance and Methicillin Sensitive Staphylococcus Aureus from Various Clinical Specimens in Tertiary Care Hospital
Author(s) | Chaitrali S Marulkar, Harsha V Patil |
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Country | India |
Abstract | INTRODUCTION : Staphylococcus aureus is one of the most common Gram-positive pyogenic bacteria responsible for variety of disease. Methicillin resistance Staphylococcus aureus (MRSA) has become a major cause of hospital associated infection. MRSA can also acquire resistance to multiple alternative antimicrobials, further complicating treatment of infection. For the severe infection of MRSA, vancomycin considered one of the last treatments relatively new agents such as Linezolid and Daptomycin is used. MATERIAL AND METHODS: 141 Staphylococcus aureus were isolated from samples such as pus, sputum, urine, blood, body fluid, wound swab received in microbiology department of Krishna institute of medical sciences, karad. They were conformed by microscopy, culture, and biochemical reaction. Then MRSA were detected by using disc diffusion test using cefoxitin (30ug) disc. RESULTS: Majority of Staphylococcus aureus were isolated from pus samples 71 (50.35%). Out of 141 isolates, 81 (57.44%) were MRSA and 60 (42.55%) were MSSA. In MRSA and MSSA isolates, higher percentage of resistance was seen in Penicillin 78 (96.29%) and 55 (90.16%) respectively. CONCLUSION :The present study emphasized the burden of MRSA in patients at our hospital. The determination of antibiotic sensitivity patterns and screening for MRSA among Staphylococcus aureus isolates are important for controlling the clinical Staphylococcal infection. The antibiotic sensitivity pattern helps in judicious use of antimicrobial agents. |
Keywords | Staphylococcus aureus, Methicillin resistance Staphylococcus aureus (MRSA), Antibiotic |
Field | Medical / Pharmacy |
Published In | Volume 6, Issue 2, March-April 2024 |
Published On | 2024-04-07 |
Cite This | Detection of Methicillin Resistance and Methicillin Sensitive Staphylococcus Aureus from Various Clinical Specimens in Tertiary Care Hospital - Chaitrali S Marulkar, Harsha V Patil - IJFMR Volume 6, Issue 2, March-April 2024. DOI 10.36948/ijfmr.2024.v06i02.16707 |
DOI | https://doi.org/10.36948/ijfmr.2024.v06i02.16707 |
Short DOI | https://doi.org/gtqxxm |
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E-ISSN 2582-2160
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IJFMR DOI prefix is
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