Anti-asthma Activity of Naturally Occurring Carbazole Alkaloids and Their Derivatives

Author(s)	Mumu Chakraborty
Country	India
Abstract	Murrayakoenigii and Glycosmispentaphylla are rich sources of carbazole alkaloids. Some of these carbazole alkaloids have shown potent biological activities. In the present work, three different derivatives of the naturally occurring carbazole alkaloid murrayanine 7 were prepared in search of bioactive organic substances. One of the carbazole alkaloids among these have shown potent anti-asthma activitycomparable to the known PDE4 inhibitor, rolipram. This paper is on isolation, characterisation, derivative preparation and determination of biological activities of some carbazole alkaloids obtained from these two plants.
Keywords	Murrayakoenigii, Glycosmispentaphylla, Carbazole alkaloids, Anti-asthma activity
Field	Chemistry
Published In	Volume 5, Issue 1, January-February 2023
Published On	2023-02-25
DOI	https://doi.org/10.36948/ijfmr.2023.v05i01.1702
Short DOI	https://doi.org/grtwnf

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