Use of Phenolic Compound as Anti-inflammatory

Pranjal Jadhav; Vineet Kadam; Sakshi Dhamne; Aarti Jagtap; Jidnyasa Narayankar

doi:10.36948/ijfmr.2024.v06i02.18236

Use of Phenolic Compound as Anti-inflammatory

Author(s)	Pranjal Jadhav, Vineet Kadam, Sakshi Dhamne, Aarti Jagtap, Jidnyasa Narayankar
Country	India
Abstract	The most prevalent secondary metabolites in plants are phenolic compounds, which have drawn increasing interest in recent years due to their diverse biological actions. One significant source of novel bioactive chemicals is natural products. Among these are phenolic chemicals, which are found in large quantities in plants and are reported to have a variety of medicinal uses. anti-inflammatory properties of phenolic-rich extracts made from round purple beans (RPB) and white kidney beans (WKB), two varieties of common beans. WKB extracts included more phenolic acids than RPB extracts, which had larger quantities of these chemicals. Moreover, RPB extracts demonstrated increased anti-inflammatory efficacy by lowering NO generation and LPS-stimulated macrophage cytokine mRNA expression. When biological, chemical, or physical agents enter the body and disrupt tissue homeostasis, the immune system releases a number of pro-inflammatory mediators. However, when these mediators are produced excessively, as happens in chronic inflammation, it may lead to further damage. Extraction, isolation of four compounds, namely (1–4), 3-O-coumaroylquinic acid (1), 3-O-feruloylquinic acid (2), 4-O-feruloylquinic acid (3), and 5-O-feruloylquinic acid (4) from Pleioblastus amarus shoots for phenolic compound. The body's immune system produces a number of pro-inflammatory mediators when biological, chemical, or physical agents disrupt tissue homeostasis. However, when this happens repeatedly, as in chronic inflammation, the immune system's overproduction of these mediators can result in the development of a number of chronic diseases.
Keywords	cytokine,phenolic-rich,anti-inflammatory,
Field	Biology > Medical / Physiology
Published In	Volume 6, Issue 2, March-April 2024
Published On	2024-04-30
Cite This	Use of Phenolic Compound as Anti-inflammatory - Pranjal Jadhav, Vineet Kadam, Sakshi Dhamne, Aarti Jagtap, Jidnyasa Narayankar - IJFMR Volume 6, Issue 2, March-April 2024. DOI 10.36948/ijfmr.2024.v06i02.18236
DOI	https://doi.org/10.36948/ijfmr.2024.v06i02.18236
Short DOI	https://doi.org/gts4tb

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Use of Phenolic Compound as Anti-inflammatory

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