International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

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Unravelling the Complexities of Inoperable Glioblastoma Multiforme: A Comprehensive Review of Current Strategies and Future Directions

Author(s) Ishaan Bakshi, Mallika Manish Pamnani, Hriday Singh Rawat
Country India
Abstract Glioblastoma multiforme (GBM) remains one of the most challenging brain tumors to treat, particularly when surgical resection is not feasible due to tumor location or patient health status. This review explores recent advances and emerging therapeutic strategies for managing inoperable GBM. Current approaches encompass a combination of targeted molecular therapies, immunotherapy, and novel drug delivery systems to enhance efficacy while minimizing systemic toxicity. Moreover, the integration of advanced imaging techniques and precision medicine holds promise in identifying patient-specific vulnerabilities and tailoring treatments accordingly. Despite significant progress, the development of resistance mechanisms and tumor heterogeneity continue to pose formidable obstacles. Hence, future directions emphasize the exploration of innovative combinatorial therapies, including immunomodulatory agents and gene editing technologies, alongside ongoing efforts to unravel the molecular intricacies driving GBM progression. Through a comprehensive understanding of the tumor microenvironment and the dynamic interplay between tumor cells and the immune system, novel therapeutic paradigms aim to redefine the treatment landscape and improve outcomes for patients with inoperable GBM.
Field Medical / Pharmacy
Published In Volume 6, Issue 2, March-April 2024
Published On 2024-04-30
Cite This Unravelling the Complexities of Inoperable Glioblastoma Multiforme: A Comprehensive Review of Current Strategies and Future Directions - Ishaan Bakshi, Mallika Manish Pamnani, Hriday Singh Rawat - IJFMR Volume 6, Issue 2, March-April 2024. DOI 10.36948/ijfmr.2024.v06i02.19244
DOI https://doi.org/10.36948/ijfmr.2024.v06i02.19244
Short DOI https://doi.org/gts4pn
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