International Journal For Multidisciplinary Research

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Review on Targeted Drug Delivery System and its Carriers as Drug Targeted to a Specific Organ

Author(s) Magar Ganesh Machindra, Pawar Priti Sanjay, Kakade Swati Babasaheb, Pawar Sakshi Nandkumar
Country India
Abstract Targeted delivery combined with controlled drug release has a pivotal function in the future of personalized medicine. Target drug delivery system is one of the most considerable novel approach towards drug delivery system. Targated drug delivery seeks to concentrate the medication in the tissues of interest while reducing the relative concentration of the medication in the ultimate tissues thus enhancing therapeutic index and bioavailability at site specific-delivery .Now a days various carrier systems which includes liposomes, niosomes, aquasomes,pharmacosomes, dendrimers, nanoparticles, microspheres, solid lipid nanoparticles, resealed erythrocytes etc. are utilized in target drug delivery system which provide site specific drug delivery. Drug targeting is the principle by which the distribution of drug in organism is maneuverer in manner such that its major fraction interacts exclusively with the target tissue at the cellular and subcellular. The present review deals with the Targeted drug delivery system its advantages, disadvantages, need of Targeted drug delivery system, Types, drug targeted to a specific organ such as Brain, kidney, heart, colon and respiratory tract and research update on Targeted drug delivery system. Various drug carriers which can be used in this advance delivery system are Niosomes, Liposomes, Nanoparticles, Monoclonal Antibodies.
Keywords Targated Drug Delivery System, TDDS, Drug Carriers, Liposomes, Niosomes, Nanoparticles, Blood Brain Barrier (BBB), Immunoglobulin (lg)
Field Medical / Pharmacy
Published In Volume 5, Issue 2, March-April 2023
Published On 2023-03-23
Cite This Review on Targeted Drug Delivery System and its Carriers as Drug Targeted to a Specific Organ - Magar Ganesh Machindra, Pawar Priti Sanjay, Kakade Swati Babasaheb, Pawar Sakshi Nandkumar - IJFMR Volume 5, Issue 2, March-April 2023. DOI 10.36948/ijfmr.2023.v05i02.1973
DOI https://doi.org/10.36948/ijfmr.2023.v05i02.1973
Short DOI https://doi.org/gr2kng
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