International Journal For Multidisciplinary Research

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Rising from the Abyss: Exploring the Lazarus Effect in Post-cardiac Arrest Spontaneous Resuscitation

Author(s) Ishaan Bakshi, Mallika Manish Pamnani, Hriday Singh Rawat
Country India
Abstract Autoresuscitation refers to the heart's ability to spontaneously regain activity and restore circulation, a concept first elucidated by K. Linko in 1982 following discontinued cardiopulmonary resuscitation (CPR). J.G. Bray coined the term "Lazarus phenomenon" in 1993, drawing from the biblical account of Lazarus being resurrected by Jesus four days after his death. By the end of 2022, 76 cases of spontaneous recovery after death had been documented worldwide, with 10 cases involving children. The range of patients spanned from a 9-month-old infant to a 97-year-old individual. Resuscitation efforts varied in duration from 6 minutes to a maximum of 90 minutes, occurring both within and outside medical facilities. Many patients had underlying health conditions, and the majority experienced non-shockable rhythms (such as Asystole or Pulseless Electrical Activity) during cardiac arrest. Survival periods post-resuscitation ranged from minutes to months, with six patients achieving full recovery without neurological deficits. Various factors contributing to autoresuscitation include hyperventilation-induced alkalosis, auto-PEEP, delayed drug effects, hypothermia, intoxication, metabolic disorders like hyperkalemia, and undetected minimal signs of life. To prevent Lazarus Syndrome, it is advised to monitor patients for at least 10 minutes after halting CPR. Raising awareness of this phenomenon within the medical community is crucial for enhancing case reporting. The likelihood of autoresuscitation appears feasible, especially among older individuals.
Field Medical / Pharmacy
Published In Volume 6, Issue 3, May-June 2024
Published On 2024-05-16
Cite This Rising from the Abyss: Exploring the Lazarus Effect in Post-cardiac Arrest Spontaneous Resuscitation - Ishaan Bakshi, Mallika Manish Pamnani, Hriday Singh Rawat - IJFMR Volume 6, Issue 3, May-June 2024. DOI 10.36948/ijfmr.2024.v06i03.20446
DOI https://doi.org/10.36948/ijfmr.2024.v06i03.20446
Short DOI https://doi.org/gtvtzn
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