International Journal For Multidisciplinary Research

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Unveiling Garlic's Arsenal: A Comprehensive Review of Antifungal and Antibacterial Cream

Author(s) Pranali Kunteshwar Rabade, Rajesh Z. Mujariya, Manjeet Singh
Country India
Abstract Garlic (Allium sativum) has long been recognized for its medicinal properties, particularly its antimicrobial effects. In this comprehensive review, we explore the therapeutic potential of garlic in the formulation of creams targeting fungal and bacterial infections. We discuss the rising prevalence of fungal infections, particularly those caused by Candida species, and the challenges they pose in healthcare settings. Furthermore, we delve into the diverse biochemical composition of garlic, including sulfur compounds, enzymes, carbohydrates, minerals, amino acids, flavonoids, and vitamins, which contribute to its antimicrobial activity. The synthesis of allicin, a key bioactive compound in garlic, and its mechanism of action against various pathogens are elucidated. Additionally, we examine the dermatological applications of topical garlic in treating fungal skin infections, wound healing, antioxidant protection, UVB shielding, and anti-aging benefits. Clinical evidence supporting the efficacy of garlic extracts in managing viral skin conditions is also discussed. Finally, we highlight the need for further research and clinical trials to fully explore garlic's therapeutic potential, safety profile, and optimal formulations, thereby enhancing patient outcomes in the management of infectious diseases.
Keywords Garlic, A.sativum, Antifungal
Field Medical / Pharmacy
Published In Volume 6, Issue 3, May-June 2024
Published On 2024-05-17
Cite This Unveiling Garlic's Arsenal: A Comprehensive Review of Antifungal and Antibacterial Cream - Pranali Kunteshwar Rabade, Rajesh Z. Mujariya, Manjeet Singh - IJFMR Volume 6, Issue 3, May-June 2024. DOI 10.36948/ijfmr.2024.v06i03.20538
DOI https://doi.org/10.36948/ijfmr.2024.v06i03.20538
Short DOI https://doi.org/gtvtxr
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