“A Study on Clinico - Biochemical Correlation Between Polycystic Ovarian Syndrome, Dyslipidemia and Insulin Resistance”

Shakti Suslade; Amita Shukla; Sangita Paneri; Angurbala Bafna

doi:10.36948/ijfmr.2024.v06i03.21359

“A Study on Clinico - Biochemical Correlation Between Polycystic Ovarian Syndrome, Dyslipidemia and Insulin Resistance”

Author(s)	Shakti Suslade, Amita Shukla, Sangita Paneri, Angurbala Bafna
Country	India
Abstract	Polycystic Ovary Syndrome (PCOS) has been recognized as an endocrine disease with re-productive and metabolic disturbances and present in 5to10% of reproductive age women. PCOS are multifactorial and polygenic. Hyperinsulinemia or Insulin resistance is key patho-genic factors in PCOS women and leads to hyperglycemia that characterized by metabolic disorders involves lipids, carbohydrates, proteins metabolism and reproductive abnormali-ties. Insulin resistance, hyperglycemia and dyslipidemia are markers of abnormal vascular function which causes increased risk of diabetes and cardiovascular disease in PCOS wom-en. The purpose of this study was to estimate insulin level and its impact on fasting glucose level, lipid profile in PCOS and PCOS related complications. Study was carried out in M.G.M. Medical college, Govt. Holkar Science college and K.R.G’s Blessed Mom Centre from December -2016 to December -2017. The study popu-lation consisted of total 60 women subject among them 30 women cases suffering from PCOS aged between 30 to 40 year taken as case group and 30 age matched healthy women taken as control group. Fasting blood sample was collected from each subject and analyzed for insulin level, fasting glucose level and Lipid profile. Results Revealed that significant increased serum Insulin, fasting glucose level, Cho-lesterol, triglycerides, LDL, VLDL levels and decreased HDL levels were observed in PCOS cases when compared to control subjects . Study concluded increase insulin level leads to increased risk of Polycystic Ovarian Syndrome and PCOS associated complications.
Keywords	: Polycystic Ovarian Syndrome(PCOS), Lipid profile, Insulin resistance, Metabolic syn-drome etc.
Field	Biology > Zoology
Published In	Volume 6, Issue 3, May-June 2024
Published On	2024-06-01
Cite This	“A Study on Clinico - Biochemical Correlation Between Polycystic Ovarian Syndrome, Dyslipidemia and Insulin Resistance” - Shakti Suslade, Amita Shukla, Sangita Paneri, Angurbala Bafna - IJFMR Volume 6, Issue 3, May-June 2024. DOI 10.36948/ijfmr.2024.v06i03.21359
DOI	https://doi.org/10.36948/ijfmr.2024.v06i03.21359
Short DOI	https://doi.org/gtw6sc

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“A Study on Clinico - Biochemical Correlation Between Polycystic Ovarian Syndrome, Dyslipidemia and Insulin Resistance”

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