International Journal For Multidisciplinary Research

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A Use of Medicinal Plant with Transfersome as avesicular Carrier that Increase the Permeation

Author(s) Mayuri Balu Jagtap, Mr.Vaibhavkumar Bapu Bhagwat
Country India
Abstract Transfersomes are a novel type of vesicular drug carrier system. Phospholipid, surfactant, and water combine to form transfersomes, which improve the transdermal medication delivery mechanism. Elastic or malleable vesicles are the shape of transfersomes.increase the transdermal distribution of bioactives.In the present study Vitex negundo loaded Transfersomes are preparedby using thin hydration technique.Vitex negundo have anti-inflammatory properties.The topical Transfersome gel is prepared. The phytochemical components of the plant extract from Vitex negundo were examined in this study using TLC and UV research. In a preliminary phytochemical analysis, flavonoids, saponins, cardiac glycoside, terpenoids, quinones, alkaloids, and tannins were discovered. Chloroform, methanol, ethyl acetate, cyclohexane, and acetic acid were combined in a ratio of 10:2:5:1:1 for TLC, and the Rf value was ascertained. A spot was found using TLC analysis, and its Rf value was 0.70. By using UV-Vis spectroscopy, the existence of an absorption peak at 640 nm was confirmed.
Keywords Vitex negundo, Transfersomes, Thin hydration technique, gel
Field Medical / Pharmacy
Published In Volume 6, Issue 3, May-June 2024
Published On 2024-06-02
Cite This A Use of Medicinal Plant with Transfersome as avesicular Carrier that Increase the Permeation - Mayuri Balu Jagtap, Mr.Vaibhavkumar Bapu Bhagwat - IJFMR Volume 6, Issue 3, May-June 2024. DOI 10.36948/ijfmr.2024.v06i03.21779
DOI https://doi.org/10.36948/ijfmr.2024.v06i03.21779
Short DOI https://doi.org/gtxrp9
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