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International Journal For Multidisciplinary Research
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Diagnostic Criteria for Uterine Sarcoma: Review of the Literature
Author(s) | allae eddine bouchaib, SOUKAINA LAAREJ, abdellah BABAHABIB, moulay el mehdi ELHASSANI, jaouad KOUACH |
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Country | Morocco |
Abstract | Uterine leiomyosarcomas are rare and have a poor prognosis, particularly at the metastatic stage. The rarity of this tumor justifie that patients be referred to referral centers afin order to have optimal diagnostic and therapeutic management. Anatomopathologic diagnosis is based on the demonstration of three features: necrosis, cytologic atypia, and mitoses within a smooth muscle proliferation. Chemotherapy probably has a place in the adjuvant management. In locally advanced or metastatic forms, the prognosis is poor, with an overall survival of about 12-14 months despite first-line polychymic therapy that gives response rates of about 30%. Anti-angiogenic drugs and hormone therapy have their place in the therapeutic arsenal. Multimodal management can improve the prognosis of some patients |
Keywords | uterine leiomyosarcoma, rare disease, chemotherapy, multidisciplinarity |
Field | Medical / Pharmacy |
Published In | Volume 5, Issue 2, March-April 2023 |
Published On | 2023-04-16 |
Cite This | Diagnostic Criteria for Uterine Sarcoma: Review of the Literature - allae eddine bouchaib, SOUKAINA LAAREJ, abdellah BABAHABIB, moulay el mehdi ELHASSANI, jaouad KOUACH - IJFMR Volume 5, Issue 2, March-April 2023. DOI 10.36948/ijfmr.2023.v05i02.2472 |
DOI | https://doi.org/10.36948/ijfmr.2023.v05i02.2472 |
Short DOI | https://doi.org/gr5qsx |
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E-ISSN 2582-2160
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IJFMR DOI prefix is
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