Formulation and Evaluation of Herbal Floating Tablet for the Treatment of Gastric Ulcer

Mr. Gaurav B. Rathod; Mr. Vaibhav V. Deshpande; Ms. Shubhangi P. Manwar

doi:10.36948/ijfmr.2023.v05i02.2591

Formulation and Evaluation of Herbal Floating Tablet for the Treatment of Gastric Ulcer

Author(s)	Mr. Gaurav B. Rathod, Mr. Vaibhav V. Deshpande, Ms. Shubhangi P. Manwar
Country	India
Abstract	Introduction: The goal of the current study was to create and assess herbal floating tablet that would treat stomach ulcers. Many of the medications that are currently on the market have either been directly or indirectly produced from plants, which have long been considered an experimental source of medication. Different diseases are treated with plant extracts. There are so many chemically active components in plants that can be used to cure so many different diseases. Herbal floating tablet increase bioavailability, extend the period that pharmaceuticals stay in the stomach, and make it easier to administer medications locally to the stomach. For the treatment of gastric ulcers, floating tablets with alcoholic extract of amla as the primary active ingredient were created in this study. Method: The herbal floating tablet was made using the direct compression method and contains alcoholic extracts of amla, aqueous extracts of ginger and fenugreek, psyllium husk, HPMC K100M, sodium bicarbonate, talc, and magnesium stearate. Additional evaluation tests for the herbal floating tablet include those for hardness, thickness, diameter, weight uniformity, and buoyancy duration. The use of buoyancy time improved the formulation. The tablet were made using the direct compression process and contained alcoholic extract of amla, aqueous extract of ginger and fenugreek, psyllium husk, HPMC K100M, sodium bicarbonate, talc, and magnesium stearate. For gastro retentive drug delivery systems, a combination of psyllium husk, sodium bicarbonate, and HPMC K100M can prove promising.
Keywords	Herbal floating tablet, amla, fenugreek, buoyancy time, HPMC K100M, Psyllium husk, ginger, Gastric ulcer.
Field	Medical / Pharmacy
Published In	Volume 5, Issue 2, March-April 2023
Published On	2023-04-24
Cite This	Formulation and Evaluation of Herbal Floating Tablet for the Treatment of Gastric Ulcer - Mr. Gaurav B. Rathod, Mr. Vaibhav V. Deshpande, Ms. Shubhangi P. Manwar - IJFMR Volume 5, Issue 2, March-April 2023. DOI 10.36948/ijfmr.2023.v05i02.2591
DOI	https://doi.org/10.36948/ijfmr.2023.v05i02.2591
Short DOI	https://doi.org/gr6h7w

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Formulation and Evaluation of Herbal Floating Tablet for the Treatment of Gastric Ulcer

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