Formulation and Evaluation of Ceftazidime Chewable Tablets

Author(s)	Shalini Sharma, Deovrat kumar
Country	India
Abstract	Antimicrobial agents are among the most commonly used and misused of all drugs. The inevitable consequence of the widespread use of antimicrobial agents has been the emergence of antibiotic-resistant pathogens, feeling an ever-increasing need for new drugs. The Cephalosporin antibiotics are useful and frequently prescribed antimicrobial agents that share a common structure and mechanism of action ¾ inhibition of synthesis of the bacterial peptidoglycan cell wall. The β-lactams also include the cephalosporin antibiotics. Cephalosporium acremonium, the first source of the cephalosporins, was isolated in 1948 by Brotzu from the sea near a sewer outlet off the Sardinian coast. by determining the Quality assurance parameters during manufacturing, which influence the dissolution behavior of the drug hence its bioavailability. The formulation and evaluation done after the survey of literature, it shows the better result rather than first and second class of cephalosporin as chewable tablets.
Keywords	Antimicrobials, cephalosporin chewable tablets, Peptidoglycan, Penicillin binding proteins, Cephalosporium acremonium
Field	Medical / Pharmacy
Published In	Volume 6, Issue 4, July-August 2024
Published On	2024-08-14
DOI	https://doi.org/10.36948/ijfmr.2024.v06i04.25937
Short DOI	https://doi.org/gt65dt

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