International Journal For Multidisciplinary Research

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Overview of Biological Activities and Synthesis of Schiff Base

Author(s) Shraddha dubey, Dr Sarita chourisia
Country India
Abstract The compounds with the azomethine group (-HC=N-) are known as schiff bases.when a primary amine condenses with an aldehyde or ketone.In most cases, heat or acid/base catalysis are used to form Schiff bases. The typical Schiff bases are basic crystalline solids, while some of them can take the form of insoluble salts that are strongly acidic. Schiff bases are employed as ligands to prepare metal complexes with a variety of distinct structures or as intermediates in the synthesis of amino acids. The inhibition of specific diseases, enzymes, or DNA replication is facilitated by the strong binding affinity of the C=N imine bond, where the electrophilic carbon and nucleophilic nitrogen effectively interact with a variety of nucleophiles and electrophiles.These Schiff bases are made from different aldehydes and amines in the following ways: stirring, catalyst-free, reflux, microwave irradiation, and ultrasonic. Both the chemical and pharmaceutical sectors use these molecules for a variety of purposes. These substances have a number of biological properties, such as antibacterial, anti-inflammatory, antiviral, and antioxidant properties. In addition to having therapeutic qualities, Schiff base molecules are crucial ligands in coordination chemistry. As a result, Schiff bases and their derivatives have the potential for use in a broad spectrum of important biological applications.
Field Chemistry
Published In Volume 6, Issue 4, July-August 2024
Published On 2024-08-14
Cite This Overview of Biological Activities and Synthesis of Schiff Base - Shraddha dubey, Dr Sarita chourisia - IJFMR Volume 6, Issue 4, July-August 2024. DOI 10.36948/ijfmr.2024.v06i04.26078
DOI https://doi.org/10.36948/ijfmr.2024.v06i04.26078
Short DOI https://doi.org/gt65bx
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