International Journal For Multidisciplinary Research

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In-silico Pharmacological Assessment of Pueraria tuberosa DC

Author(s) Aarcha Jayakishore, Atul Thorat
Country India
Abstract Pueraria tuberosa DC, a traditional medicinal herb, is widely recognised for its therapeutic benefits. The study aims to estimate the pharmacological probability of its phytocompounds through an extensive ADME (Absorption-Distribution-Metabolism-Excretion) investigation. We discovered substantial bioactive compounds in Pueraria tuberosa using the online database IMPPAT (Indian Medicinal Plants, Phytochemistry, and Therapeutics). Our analysis revealed a miscellaneous range of chemical constituents with excellent pharmacological profiles, indicating favourable absorption and distribution properties. The findings accentuate the therapeutic value of Pueraria tuberosa, validating its historic use in the management of various diseases. This study corroborates the foundation for further research and drug development efforts by emphasizing the pharmacological properties of its phytochemicals. We conducted a detailed examination of the phytocompounds discovered in Pueraria tuberosa, comparing fourteen compounds based on ADME features such as lipophilicity, water solubility, medicinal chemistry, pharmacokinetics, and drug-likeness. Overall, this study advocates for further exploration into Pueraria tuberosa as a potential candidate for the development of herbal-based medicines, thereby contributing to the emergent interest in phytomedicine and the quest for novel therapeutic agents.
Keywords ADME, IMPPAT, Pharmacological, Phytomedicine, Phytocompounds, Pueraria tuberosa, Therapeutic agents.
Field Biology
Published In Volume 6, Issue 4, July-August 2024
Published On 2024-08-19
Cite This In-silico Pharmacological Assessment of Pueraria tuberosa DC - Aarcha Jayakishore, Atul Thorat - IJFMR Volume 6, Issue 4, July-August 2024. DOI 10.36948/ijfmr.2024.v06i04.26291
DOI https://doi.org/10.36948/ijfmr.2024.v06i04.26291
Short DOI https://doi.org/gt7m4h
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