International Journal For Multidisciplinary Research

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Alzheimer's Disease and Its a Diagnosis, Symptoms, Pathophysiology, and Treatment

Author(s) Devram B. Sodha, Devang H. Joshi, Dhruvik B. Joshi, Rajesh M. Vala, Dharmesh R. Makvana
Country India
Abstract Alzheimer’s disease (AD) is the most prevalent form of dementia, predominantly affecting individuals over 65 years old, though a rare form can manifest in younger people. Globally, AD accounts for approximately 75% of the more than 35 million dementia cases, with projections suggesting the number could rise to 115 million by 2050. The precise etiology of Alzheimer’s remains largely unknown. Historically, dementia has been recognized since ancient times, with significant milestones in understanding and terminology occurring from the 17th century onwards. Alzheimer’s disease is identified by symptoms such as confusion, personality changes, language difficulties, mood swings, and short-term memory disturbance. Pathophysiologically, AD is characterized by amyloid plaques and neurofibrillary tangles (NFTs) which cause brain damage. Diagnosis involves clinical evaluation, neuroimaging, neuropathological findings, and cerebrospinal fluid analysis. Risk factors include genetic predisposition, vascular issues, and psychosocial elements. Current treatments focus on acetylcholinesterase inhibitors to manage symptoms, particularly in the mild to moderate stages of the disease.
Keywords Alzheimer's disease(AD), diagnosis, symptoms, risk factors, and treatment, dementia.
Field Medical / Pharmacy
Published In Volume 6, Issue 5, September-October 2024
Published On 2024-09-27
Cite This Alzheimer's Disease and Its a Diagnosis, Symptoms, Pathophysiology, and Treatment - Devram B. Sodha, Devang H. Joshi, Dhruvik B. Joshi, Rajesh M. Vala, Dharmesh R. Makvana - IJFMR Volume 6, Issue 5, September-October 2024. DOI 10.36948/ijfmr.2024.v06i05.27483
DOI https://doi.org/10.36948/ijfmr.2024.v06i05.27483
Short DOI https://doi.org/g59zw2
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