International Journal For Multidisciplinary Research

E-ISSN: 2582-2160     Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 6 Issue 5 September-October 2024 Submit your research before last 3 days of October to publish your research paper in the issue of September-October.

Exploring Multiple Endocrine Neoplasia Type 2B: Key Findings from a Case Report

Author(s) Hayat Aynaou, Houda Salhi
Country Maroc
Abstract Multiple endocrine neoplasia type 2B (MEN 2B) is an autosomal dominant syndrome primarily caused by the germline M918T RET mutation. It is characterized by medullary thyroid carcinoma (MTC), pheochromocytoma (PC), and non-endocrine features. Symptoms depend on the glandular elements present. The initial diagnosis of MEN 2B is relatively late, and the diagnosis by non-endocrine components is extremely weak. The initial management consists of a total thyroidectomy with dissection of the lymph nodes. If PC is present, its treatment is surgical removal, which should be performed before thyroidectomy for MTC. The prognosis of MTC in MEN 2B depends on the stage at diagnosis, and only early diagnosis and intervention offer a chance of cure. It is necessary to underline the need to treat the extra-endocrine signs in these patients. We present below a case of MEN 2B who consulted late for a cervical tumor and morphological abnormalities of the lips and tongue.
Keywords MEN 2B, medullary thyroid carcinoma, pheochromocytoma, RET mutation
Field Médical / Pharmacie
Published In Volume 6, Issue 5, September-October 2024
Published On 2024-09-22
Cite This Exploring Multiple Endocrine Neoplasia Type 2B: Key Findings from a Case Report - Hayat Aynaou, Houda Salhi - IJFMR Volume 6, Issue 5, September-October 2024. DOI 10.36948/ijfmr.2024.v06i05.27632
DOI https://doi.org/10.36948/ijfmr.2024.v06i05.27632
Short DOI https://doi.org/g4qmp5

Share this