International Journal For Multidisciplinary Research

E-ISSN: 2582-2160     Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 6 Issue 5 September-October 2024 Submit your research before last 3 days of October to publish your research paper in the issue of September-October.

Comparing the Antibacterial Efficacy of Morus Alba (Mulberry Leaf) Extract and 0.2% Chlorhexidine: An Invitro Assay

Author(s) Subodh Kumar, Rajkumari Surbala Devi, Rejita Nongmeikapam
Country India
Abstract Background: Morus Alba is being used for the treatment of diabetes to reduce blood sugar levels. It has also shown antimicrobial and anti-inflammatory activity against Candida albicans, Saccharomyces cerevisiae, Escherichia coli, Salmonella typhimurium, Staphylococcus epidermis, and S. aureus. Extracts of the bark of Morus alba have also shown bactericidal activity against the oral Streptococci.
Aim: To compare the antibacterial efficacy of Morus Alba (mulberry leaf) extract with 0.2% chlorhexidine gluconate mouthwash.
Material & methods: The Morus Alba aqueous leaf extraction was carried out by using the hot maceration technique with deionised water, and the minimal inhibition concentration (MIC) of the of the Morus Alba aqueous leaf extract was evaluated against the biofilm-forming Streptococcus mutans.
Results: The minimal inhibition concentration (MIC) of hot methanol extract of Morusalba (2.5 mg/ 10 ml) was used to study its effect on bacterial growth. As the concentration of Morus Alba aqueous leaf extract increases, the OD values decrease, indicating reduced bacterial growth. The reduction percentage increases with higher concentrations of leaf extract, showing a dose-dependent inhibition of Streptococcus mutans. The 0.2% CHX shows the highest reduction, confirming its effectiveness.
Conclusion: The aqueous extract of Morus Alba mouthwash shows a significant inhibitory effect on Streptococcus mutans, with higher concentrations leading to a greater reduction in bacterial growth.
Keywords Mulberry leaf Extract, Mouthwash, Aqueous, Antibacterial efficacy
Field Medical / Pharmacy
Published In Volume 6, Issue 5, September-October 2024
Published On 2024-09-28
Cite This Comparing the Antibacterial Efficacy of Morus Alba (Mulberry Leaf) Extract and 0.2% Chlorhexidine: An Invitro Assay - Subodh Kumar, Rajkumari Surbala Devi, Rejita Nongmeikapam - IJFMR Volume 6, Issue 5, September-October 2024. DOI 10.36948/ijfmr.2024.v06i05.28090
DOI https://doi.org/10.36948/ijfmr.2024.v06i05.28090
Short DOI https://doi.org/g59zr9

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