International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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Oral & Intra Tympanic Corticosteroid effect on Sudden Hearing Loss & Suppressing Tinnitus: A Pilot Study

Author(s) Shrutinath Banerjee
Country India
Abstract Systemic glucocorticosteroids (“steroids”) are widely used worldwide as a standard of care for primary therapy of idiopathic sudden sensorineural hearing loss (ISSHL). The German ISSHL guideline recommends high-dose steroids without evidence from randomized controlled trials (RCTs) and refers solely to retrospective cohort studies. This RCT aims to assess the efficacy (improvement in hearing) and safety (especially systemic side effects) of high-dose steroids versus standard of care (standard dose systemic steroids) for the treatment of unilateral ISSHL, when given as a primary therapy. There is an unmet medical need for an effective medical therapy of ISSHL. Although sensorineural hearing impairment can be partially compensated by hearing aids or cochlear implants (CI), generic hearing is better than using hearing aids or CIs. Since adverse effects of a short course of high-dose systemic corticosteroids have not been documented with good evidence, the trial will improve knowledge on possible side effects in the different treatment arms with a focus on hyperglycemia and hypertension.
Keywords SNHL, Sudden hearing loss, intratympanic, steroid
Field Medical / Pharmacy
Published In Volume 6, Issue 6, November-December 2024
Published On 2024-11-27
Cite This Oral & Intra Tympanic Corticosteroid effect on Sudden Hearing Loss & Suppressing Tinnitus: A Pilot Study - Shrutinath Banerjee - IJFMR Volume 6, Issue 6, November-December 2024. DOI 10.36948/ijfmr.2024.v06i06.31760
DOI https://doi.org/10.36948/ijfmr.2024.v06i06.31760
Short DOI https://doi.org/g8sdfr
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