Uniqueness of Albumin as a Carrier in Nanodrug Delivery

SACHIN A. PANDHARE; KOMAL MORE; D.K.VIR; VISHAL P. JADHAV

doi:10.36948/ijfmr.2024.v06i06.32476

Uniqueness of Albumin as a Carrier in Nanodrug Delivery

Author(s)	SACHIN A. PANDHARE, KOMAL MORE, D.K.VIR, VISHAL P. JADHAV
Country	India
Abstract	ABSTRACT In contemporary medicine, albumin nanoparticles have become a powerful and adaptable nanodrug carrier. The ability of human serum albumin to deliver hydrophobic drugs through passive and active targeting mechanisms demonstrates its versatility in treating a variety of disorders. In addition to discussing ongoing clinical trials using albumin-based formulations, this study emphasizes the benefits of albumin-bound Paclitaxel (Abraxane) over solvent-based formulations (Taxol). Future advancements in albumin-based therapeutics are made possible by the emphasis placed on the importance of albumin in improving drug performance and its potential as a drug delivery mechanism. Albumin nanoparticles show promise in the treatment of a variety of illnesses. This study emphasizes their use in the delivery of hydrophobic drugs, their benefits over formulations based on solvents, and their ongoing clinical trials. The medicinal potential of albuminNeutrophils, leveraging their inflammation-targeting capabilities, have emerged as innovative drug delivery carriers. Integrating neutrophils with nanotechnology enhances treatment efficacy and reduces side effects. This review explores neutrophil-based nano-drug delivery systems, including membrane-coated nanoparticles, cell-loaded nanoparticles, and chimeric antigen receptor (CAR)-neutrophils. These therapies demonstrate superior biocompatibility, targeting, and therapeutic robustness, showing promise in various disease treatments.Neutrophils, combined with nanotechnology, offer innovative drug delivery. This review covers design principles, mechanisms, and applications of neutrophil-based nano-drug delivery systems, highlighting enhanced biocompatibility, targeting, and therapeutic efficacy.
Keywords	Nanomedicine, albumin, nanoparticles, production method.
Field	Medical / Pharmacy
Published In	Volume 6, Issue 6, November-December 2024
Published On	2024-12-07
Cite This	Uniqueness of Albumin as a Carrier in Nanodrug Delivery - SACHIN A. PANDHARE, KOMAL MORE, D.K.VIR, VISHAL P. JADHAV - IJFMR Volume 6, Issue 6, November-December 2024. DOI 10.36948/ijfmr.2024.v06i06.32476
DOI	https://doi.org/10.36948/ijfmr.2024.v06i06.32476
Short DOI	https://doi.org/g8t3j3

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Uniqueness of Albumin as a Carrier in Nanodrug Delivery

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