International Journal For Multidisciplinary Research

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Assessment of Biochemical Risk Factors of Coronary Artery Disease in North and South Indian population

Author(s) Shashwat Singh, Suchit Swaroop
Country India
Abstract Coronary artery disease (CAD) in India is closely linked to elevated body mass index (BMI), dyslipidemia, and metabolic risk factors. Studies from Northern India, including Himachal Pradesh, Uttar Pradesh, and Jammu & Kashmir, show high obesity prevalence, especially in rural and tribal populations, with low HDL
and borderline triglyceride levels. Advanced lipid markers like oxidized LDL (ox-LDL) and small dense LDL (sdLDL) are more effective in predicting premature CAD than traditional markers. In Southern India, particularly in Kerala and Andhra Pradesh, similar trends of elevated BMI, dyslipidemia, and gender-specific risks are observed, with associations between abdominal obesity, high cholesterol, and low HDL.
Additionally, epicardial adipose tissue (EAT) thickness and lipoprotein-associated phospholipase A2 (LpPLA2) activity are identified as independent CAD predictors. Both regions share common risk factors, exacerbated by urbanization and changing lifestyles, highlighting the need for targeted public health interventions to manage CAD risk factors effectively.
Keywords Coronary Artery Disease, Biochemical studies, North India, South India.
Field Biology > Medical / Physiology
Published In Volume 7, Issue 1, January-February 2025
Published On 2025-01-19
Cite This Assessment of Biochemical Risk Factors of Coronary Artery Disease in North and South Indian population - Shashwat Singh, Suchit Swaroop - IJFMR Volume 7, Issue 1, January-February 2025. DOI 10.36948/ijfmr.2025.v07i01.34297
DOI https://doi.org/10.36948/ijfmr.2025.v07i01.34297
Short DOI https://doi.org/g82hjs
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