International Journal For Multidisciplinary Research

E-ISSN: 2582-2160     Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 7, Issue 1 (January-February 2025) Submit your research before last 3 days of February to publish your research paper in the issue of January-February.

A Case Report on Donepezil Induced Cervical Dystonia

Author(s) RANIMOL MATHEW, RINKU ELSA REJI, ARYA ABHEDANANDHAN, HARIKRISHNAN S
Country India
Abstract Cervical dystonia, is a neurological condition characterized by involuntary neck muscle contractions, abnormal head and neck postures. This case report describes a 63 Year-old male with Parkinsonism and early dementia who developed severe cervical dystonia after starting Donepezil, a cholinesterase inhibitor used to manage cognitive impairment. The patient came with complaints of difficulty in sitting, mild rigidity and anterior neck flexion. Discontinuation of Donepezil led to significant improvement; subsequent treatment with Trihexyphenidyl was effective. This case underscores the importance of monitoring for rare but serious side effects of cholinesterase inhibitors and highlights the need for further research into their mechanisms and risk factors.
Keywords Donepezil, Cervical dystonia, Parkinsonism, Trihexyphenidyl.
Field Medical / Pharmacy
Published In Volume 7, Issue 1, January-February 2025
Published On 2025-01-18
Cite This A Case Report on Donepezil Induced Cervical Dystonia - RANIMOL MATHEW, RINKU ELSA REJI, ARYA ABHEDANANDHAN, HARIKRISHNAN S - IJFMR Volume 7, Issue 1, January-February 2025. DOI 10.36948/ijfmr.2025.v07i01.35463
DOI https://doi.org/10.36948/ijfmr.2025.v07i01.35463
Short DOI https://doi.org/g82gm5

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