Bioactive Compounds of Ganoderma lucidum and their Therapeutic Applications

Khushwant Nandal; Manjeet Kaur; Jitender Rathee; Anshul Sharma

doi:10.36948/ijfmr.2023.v05i03.3982

Bioactive Compounds of Ganoderma lucidum and their Therapeutic Applications

Author(s)	Khushwant Nandal, Manjeet Kaur, Jitender Rathee, Anshul Sharma
Country	India
Abstract	Ganoderma lucidum(GL), a renowned medicinal mushroom has been traditionally used in Korea, China and Japan to promote longevity, enhance vitality, and treat various ailments. It is referred to as "God's herb" in ancient China, and has been cultivated extensively on sawdust and wood logs in response to demand in global market. Extensive in vivo and in vitro investigations have elucidated the manifold metabolic activities of GL. It has been found to contain a wide array of biochemical compounds such as fatty acids, triterpenoids, nucleosides, polysaccharides, amino acids, proteins, and enzymes, all of which possess significant pharmacological properties. Triterpenoids and polysaccharides from G. lucidum have exhibited antiangiogenic, cytotoxic, anti-allergic, hepatoprotective, antioxidant, anti-hypertensive, hypocholesterolemic, hypoglycemic, antimicrobial, anti-inflammatory, antitumor, immuno-modulatory, and antihistamine effects. G.lucidum alongwith array of medicinal properties also possess certain limitations to be addressed. Clinical trials frequently encounter obstacles concerning the absence of pure constituents and the precise identification of obtained compounds, which can pose challenges in the research process. Furthermore, most of the included studies were of small scale, raising concerns about their methodological quality. Although Ganoderma has shown promising potential in cancer prevention and treatment, it should not be considered as a first-line therapy for cancer. G. lucidum extracts and active compounds formulation have undergone patenting, development, and application as cosmeceuticals, pharmaceuticals and nutraceuticals. This review highlights the potential of G. lucidum as an untapped natural medicine in the management of emerging infectious diseases. However, this study does not delve into the specific chemical compounds or mode of action of each bioactive component against different emerging diseases.
Keywords	Ganoderma lucidum, bioactive compounds, medicinal, therapeutic, properties
Field	Biology > Medical / Physiology
Published In	Volume 5, Issue 3, May-June 2023
Published On	2023-06-24
Cite This	Bioactive Compounds of Ganoderma lucidum and their Therapeutic Applications - Khushwant Nandal, Manjeet Kaur, Jitender Rathee, Anshul Sharma - IJFMR Volume 5, Issue 3, May-June 2023. DOI 10.36948/ijfmr.2023.v05i03.3982
DOI	https://doi.org/10.36948/ijfmr.2023.v05i03.3982
Short DOI	https://doi.org/gsdk6k

View / Download PDF File

E-ISSN 2582-2160

doi

CrossRef DOI is assigned to each research paper published in our journal.

IJFMR DOI prefix is
10.36948/ijfmr

Downloads

Research Paper Format Copyright Permission Form and Undertaking Form Cover Page Vol 6 Isu 4 Cover Page Vol 6 Isu 3 Cover Page Vol 6 Isu 2

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA

About IJFMR Fees & Payment Current Issue Publication Archive	Submit Research Paper Track Submission Status Publication Guidelines Publication Ethics Peer Review & Plagiarism	Join as a Reviewer Editors & Reviewers Reviewer Referral Program Get Reviewer Membership Certi.	Website/Journal Policies Usage Policy Content Policies Privacy Policy

Contact Us		+91-9898-5948-55	editor@ijfmr.com

International Journal For Multidisciplinary Research

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Bioactive Compounds of Ganoderma lucidum and their Therapeutic Applications

Share this