International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 6 Issue 4 July-August 2024 Submit your research before last 3 days of August to publish your research paper in the issue of July-August.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 6 Issue 4
July-August 2024

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

Evaluation of Teratogenic Effect of Methanolic Extract of Fruits of Momordica dioica In Rat Model

Author(s) Blessy Elizabeth Babukutty, Deepak Kumar Jha, Ali Salman Al-Shami, Jeevan Khadka
Country India
Abstract Background: Teras- ‘Monster’ and Genesis- ‘Producing.’ Teratogenecity is the ability to cause fetal abnormalities when administered to the pregnant mother at any stage of pregnancy. Momordica dioica, commonly known as spiny gourd, is a species of flowering plant in the Cucurbitaceae family. It has commercial importance and is exported as well as used locally as a vegetable in all regions of India. Objective: The main objective of this research was to evaluate the teratogenic activity of methanolic extract of fruits of Momordica dioica in rat model. Methodology: The dose selection was made based on acute toxicity studies. For evaluating teratogenicity, the pregnant animals were divided into 5 groups and drug administration was done from day 6-17 of gestation. All groups were subjected to laparotomy and then were sacrificed for teratogenic examination which involves physical parameters, morphological analysis and histopathological studies of the foetuses. Results: The rats treated with methanolic extract of fruits of Momordica dioica did not show any teratogenic activity which was evident by observing the physical parameters, morphological analysis and histopathological study. Conclusion: From the results we can conclude that methanolic extract of fruits of Momordica dioica administered at a dose of 250, 500, and 1000mg/kg bodyweight was not teratogenic.
Keywords Momordica dioica fruits, teratogenicity, pregnancy, rat model, methanolic extract, histopathology.
Field Medical / Pharmacy
Published In Volume 5, Issue 4, July-August 2023
Published On 2023-08-25
Cite This Evaluation of Teratogenic Effect of Methanolic Extract of Fruits of Momordica dioica In Rat Model - Blessy Elizabeth Babukutty, Deepak Kumar Jha, Ali Salman Al-Shami, Jeevan Khadka - IJFMR Volume 5, Issue 4, July-August 2023. DOI 10.36948/ijfmr.2023.v05i04.5635
DOI https://doi.org/10.36948/ijfmr.2023.v05i04.5635
Short DOI https://doi.org/gsm4w5
View / Download PDF File

Share this


E-ISSN 2582-2160
CrossRef

CrossRef DOI is assigned to each research paper published in our journal.

IJFMR DOI prefix is
10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form Cover Page Vol 6 Isu 4 Cover Page Vol 6 Isu 3 Cover Page Vol 6 Isu 2

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9898-5948-55 editor@ijfmr.com