International Journal For Multidisciplinary Research

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Clinical Profile of Various Mnd Cases that Presented to a Tertiary Centre over the Past 3 Years

Author(s) Yatish Gujjar L, Madusudhan c, Teena chandran
Country India
Abstract INTRODUCTION:
Motor neurone disease (MND) is a disabling and ultimately fatal disease of the motor system, with few effective treatments. Considerable heterogeneity is observed in the clinical motor features of MND, with extra-motor manifestations now also recognized as part of the condition. Progressive motor weakness and bulbar dysfunction lead to premature death, usually from respiratory failure. Diagnosis remains clinical. There are no specific laboratory markers which make the diagnosis independent of the clinical pattern but there are a few appropriate investigations to exclude mimics. The clinical syndrome once observed is recognized easily because of a distinctive appearance and course.
OBJECTIVES:
To demonstrate and compare the etiology, demography & clinical profile of various forms of Motor Neuron Diseases
DESIGN:
Cross sectional (Observational) study
SETTING:
Sapthagiri Institute of Medical Sciences & Research Centre
METHODS:
30 MND cases diagnosed clinically (as per Awaji Shima modification of the El Escorial Criteria) with few supportive investigations that presented to our centre over the past 3 years were compiled and compared
CONCLUSIONS:
Mortality rates in MND depends on type of MND and subtypes like Madras Motor Neuron disease, SMA, PLS has the slowest progression and best prognosis of all the subtypes. Secondary MND due to exposure to heavy metals has faster progression and worst prognosis
Keywords Motor neuron disease, Amyotrophic lateral sclerosis, Spinal muscular atrophy
Field Medical / Pharmacy
Published In Volume 5, Issue 5, September-October 2023
Published On 2023-09-17
Cite This Clinical Profile of Various Mnd Cases that Presented to a Tertiary Centre over the Past 3 Years - Yatish Gujjar L, Madusudhan c, Teena chandran - IJFMR Volume 5, Issue 5, September-October 2023. DOI 10.36948/ijfmr.2023.v05i05.6582
DOI https://doi.org/10.36948/ijfmr.2023.v05i05.6582
Short DOI https://doi.org/gssfpb
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