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International Journal For Multidisciplinary Research
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Case Series Of Various Mixed Connective Tissue Disorder Cases That Presented To Sapthagiri Hospital Over The Past 2 Years
Author(s) | Pandhare Rushikesh Hemant, Madhusudhan C, Teena chandran |
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Country | India |
Abstract | Background: Mixed connective tissue disease (MCTD) is a rare autoimmune disease, characterized by the production of specific autoantibody anti-RNP, which presents with varied overlapping symptoms of different connective tissue disorders. The aim of this study is to identify the frequency and patterns of MCTD. Objective :To demonstrate the clinical profile,immunological profile of MCTD patients and adverse events developed during the duration of treatment Design :Prospective observational study Setting : A large, academic, tertiary medical center Methodology:All MCTD cases admitted in Sapthagiri Institute of Medical Sciences and Research Centre was included.Data was collected through a prepared performa.Patients were followed up till death or discharge. Results:All 10 cases of MCTD, U1RNP is positive. 8 of the 10 cases were treated aggressively with immunosuppressants. Most common secondary infection was Pneumonia. One patient developed Abdominal TB One patient developed avascular necrosis of femur secondary to high dose steroids. Interpretation and conclusion:It can be noted that even though the relapse rate was lower among patient treated aggressively the chance of developing secondary infection was very high Hence it is important to monitor the cases which are treated with immunosuppressants, for early diagnosis and treatment of any adverse events. |
Keywords | MCTD,Pneumonia,avascular necrosis |
Field | Medical / Pharmacy |
Published In | Volume 5, Issue 5, September-October 2023 |
Published On | 2023-09-22 |
Cite This | Case Series Of Various Mixed Connective Tissue Disorder Cases That Presented To Sapthagiri Hospital Over The Past 2 Years - Pandhare Rushikesh Hemant, Madhusudhan C, Teena chandran - IJFMR Volume 5, Issue 5, September-October 2023. DOI 10.36948/ijfmr.2023.v05i05.6764 |
DOI | https://doi.org/10.36948/ijfmr.2023.v05i05.6764 |
Short DOI | https://doi.org/gssfkk |
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