Aetiological and Clinical Profile of New Onset Seizures in Adults: An Institutional Experience

Dr. Rohit Kumawat; Dr. Neeraj Bhutani; Dr. Priya Agarwal; Dr. Prashant Gandhi

doi:10.36948/ijfmr.2022.v04i04.058

Aetiological and Clinical Profile of New Onset Seizures in Adults: An Institutional Experience

Author(s)	Dr. Rohit Kumawat, Dr. Neeraj Bhutani, Dr. Priya Agarwal, Dr. Prashant Gandhi
Country	India
Abstract	Objective: This study was conducted with the objective to identify the aetiology of first seizure in adults and to evaluate their clinical profile, treatment practices and seizure recurrence. Methods: A prospective observational study was conducted at the Neuro-sciences department of a tertiary care hospital cum medical research institute of Northern India from April-2017 to October-2018. A total of 114 adult patients aged 18 years or above, who presented to the hospital within 15 days of new onset seizures or developed first seizure in this hospital during the study period, were included in the study. Patients were followed up for 3 months to determine recurrence rate. Results: First seizure occurred before 50 years age in most patients (65%). Generalized Tonic Clonic Seizure was most common noticed type. Most patients (63.2%) had single seizure, while status epilepticus occurred in 13.2% cases. Nearly 3/4 patients had provoked seizures. Neuro-infections and systemic/metabolic causes were relatively more common in 18-29 years group, while in older age group, cerebrovascular accidents and neuro-infections were more common. Amongst the cerebrovascular causes infraction (ischemia) was the most common. Neuro-cysticercosis was the most common infection followed by Tuberculosis. Recurrence was seen in 23 (20.2%) cases during 3 months follow up. Recurrence was significantly more common in noncompliant patients and in patients with seizure cluster at initial presentation. Conclusion: Aetiology of adult new onset seizure varies with age and can vary geographically. Local etiological studies can help in early diagnosis and individualized treatment to prevent recurrence.
Keywords	New Onset Seizure, Adult Onset Seizure, Epilepsy
Field	Medical / Pharmacy
Published In	Volume 4, Issue 4, July-August 2022
Published On	2022-08-27
Cite This	Aetiological and Clinical Profile of New Onset Seizures in Adults: An Institutional Experience - Dr. Rohit Kumawat, Dr. Neeraj Bhutani, Dr. Priya Agarwal, Dr. Prashant Gandhi - IJFMR Volume 4, Issue 4, July-August 2022. DOI 10.36948/ijfmr.2022.v04i04.058
DOI	https://doi.org/10.36948/ijfmr.2022.v04i04.058
Short DOI	https://doi.org/10/gqr488

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Aetiological and Clinical Profile of New Onset Seizures in Adults: An Institutional Experience

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