International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 6 Issue 4 July-August 2024 Submit your research before last 3 days of August to publish your research paper in the issue of July-August.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 6 Issue 4
July-August 2024

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

Drug Solubility: Importance and Enhancement Techniques

Author(s) Sanika Chandrakant Deokate, Aditya Abaso deokate, Saurabh Bapu Sangale, Tejrag Popat Gawade
Country India
Abstract One of the key factors in achieving the optimum drug concentration in the systemic circulation for the desired (expected) pharmacological response is solubility, the phenomenon of solute dissolving in solvent to produce a homogeneous system. The main issue in developing formulations for new chemical entities as well as for generic development is low water solubility. Over 40% of NCES (new chemical entities) created in the pharmaceutical business are essentially water Insoluble. A significant difficulty for formulation scientists is solubility. Any medicine that is to be absorbed must be present in solution at the absorption site. Poorly soluble medications can be made more soluble using a variety of strategies, including physical and chemical drug changes and other approaches like Changed Words – Structural Changes Longest Unchanged Words particle reduction, crystal engineering, salt creation, solid dispersion, surfactant use, complexation, and other processes. The choice of a solubility-improving technique depends on the drug’s properties, the site of absorption, and the requirements for the dosage form.
Keywords solubility, homogeneous, particle size, chemical modification ,salt formulation.
Field Medical / Pharmacy
Published In Volume 5, Issue 5, September-October 2023
Published On 2023-10-07
Cite This Drug Solubility: Importance and Enhancement Techniques - Sanika Chandrakant Deokate, Aditya Abaso deokate, Saurabh Bapu Sangale, Tejrag Popat Gawade - IJFMR Volume 5, Issue 5, September-October 2023. DOI 10.36948/ijfmr.2023.v05i05.7146
DOI https://doi.org/10.36948/ijfmr.2023.v05i05.7146
Short DOI https://doi.org/gst3tq
View / Download PDF File

Share this


E-ISSN 2582-2160
CrossRef

CrossRef DOI is assigned to each research paper published in our journal.

IJFMR DOI prefix is
10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form Cover Page Vol 6 Isu 4 Cover Page Vol 6 Isu 3 Cover Page Vol 6 Isu 2

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9898-5948-55 editor@ijfmr.com