International Journal For Multidisciplinary Research

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A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

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Structural Elucidation of Some Coordination Compounds With Reference Phosphorescent Metal Composite as Theranostic Anticancer Agents

Author(s) Vijay Kumar
Country India
Abstract This paper reveals that the phosphorescent metal composite are a new kind of multifunctional antitumor compounds that can integrate imaging and antitumor functions in a single molecule. In this minireview, we summarize the recent research progress in this field, concentrating on the theranostic applications of phosphorescent iridium(III), ruthenium(II) and rhenium(I) composite. The infinitesimal design that affords these composite with tumour- or subcellular organelle-targeting properties is elucidated. The potential of these composite to induce and monitor the dynamic behavior of subcellular organelles and the changes in microenvironment during the process of therapy is demonstrated. Moreover, the potential and advantages of applying new technologies, such as super-resolution imaging and phosphorescence lifetime imaging, are also described. Finally, the challenges faced in the development of novel theranostic metallo-anticancer composite for possible clinical translation are proposed.
Keywords tumour heterogeneity, drug resistance and systemic toxicity
Field Chemistry
Published In Volume 5, Issue 5, September-October 2023
Published On 2023-10-17
Cite This Structural Elucidation of Some Coordination Compounds With Reference Phosphorescent Metal Composite as Theranostic Anticancer Agents - Vijay Kumar - IJFMR Volume 5, Issue 5, September-October 2023. DOI 10.36948/ijfmr.2023.v05i05.7343
DOI https://doi.org/10.36948/ijfmr.2023.v05i05.7343
Short DOI https://doi.org/gswg7v

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