Synthesis, Characterization and Antibacterial Screening of Amino Cyanopyridines Analogues

Author(s)	S.N.Lakhekar, G. B. Rahatikar, Seema habib, B.D.Kalyankar, M.A. Baseer
Country	India
Abstract	The new series of amino cyanopyridine derivatives were prepared from mixture of Chalcones (2.3a-i), malononitrile and ammonium acetate in ethanol. all the newly synthesized compounds were evaluated for their antibacterial action in vitro against gram +ve bacteria S. aureus, B. subtilis and gram -ve bacteria P. aeruginosa, E. coli by agar well diffusion method. The tested compounds 3.1a showed good activity against two bacterial strain viz. E. coli, P. aeruginosa and the compound 3.1b showed good antibacterial activity against all bacterial strain w.r.t penicillin as a std. drig while remaining compounds showed moderate to poor activity. The chemical structures of the compounds were proved by IR, 1H NMR, Mass, C13 NMR spectrometric data.
Keywords	amino cyanopyridine, chalcone, malononitrile, antibacterial activity.
Field	Chemistry
Published In	Volume 5, Issue 5, September-October 2023
Published On	2023-10-28
Cite This	Synthesis, Characterization and Antibacterial Screening of Amino Cyanopyridines Analogues - S.N.Lakhekar, G. B. Rahatikar, Seema habib, B.D.Kalyankar, M.A. Baseer - IJFMR Volume 5, Issue 5, September-October 2023. DOI 10.36948/ijfmr.2023.v05i05.8055
DOI	https://doi.org/10.36948/ijfmr.2023.v05i05.8055
Short DOI	https://doi.org/gs3hf9

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