International Journal For Multidisciplinary Research

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Synthesis, Characterization and Molecular Docking Studies of Novel Pteridine Derivatives

Author(s) M. Jayasree, D. Visagaperumal, Vineeth Chandy
Country India
Abstract Pteridines are a group of heterocyclic compounds which contain nitrogen as a major heteroatom and it was aromatic compounds that are attached to the pyrazine and pyrimidine ring family. Pteridine derivatives have focused on a specific place in the medicinal chemistry field. The Pteridine ring is present in several natural compounds such as Pterin, Hemiptera (erythropoietin), Biopterin, Neopterin, Xanthopterin, iso-xanthopterin, etc., which include a few heterocyclic compounds like pyrimidine, pyrazine rings. Some vitamins like folic acid and riboflavin and drugs like methotrexate and triamterene. A pteridine is formed by a condensation process. A pteridine is frequently produced using costly and dangerous chemicals. In order to reduce the cost and consumption of hazardous chemicals, novel pteridine compounds were made by mixing a catalyst with a solvent, primary amines, and phenols. Currently, the primary issue limiting a medicine's ability to effectively treat a disease includes the development of resistance. In this article, we will utilise docking studies to provide a thorough explanation of the synthesis of pteridine derivatives and their antioxidant capabilities.
Keywords Pteridine, Isay Reaction, Antioxidant, DPPH, Molecular Docking
Field Chemistry > Pharmacy
Published In Volume 4, Issue 5, September-October 2022
Published On 2022-10-02
Cite This Synthesis, Characterization and Molecular Docking Studies of Novel Pteridine Derivatives - M. Jayasree, D. Visagaperumal, Vineeth Chandy - IJFMR Volume 4, Issue 5, September-October 2022. DOI 10.36948/ijfmr.2022.v04i05.843
DOI https://doi.org/10.36948/ijfmr.2022.v04i05.843
Short DOI https://doi.org/grb58s
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