To Evaluate the Hepatoprotective Activity of Leaves of Salacia Chinensis Linn. on CCl4 Induced Albino Wistar Rats

Author(s)	Manjusha V Nikale
Country	India
Abstract	The main aim of the present study is to evaluate the Hepatoprotective activity of aqueous slurry of leaves of Salacia chinensis Linn .on CCl4 induced liver damage in rats. Hepatotoxicity was induced by CCl4 and the biochemical parameters such as serum glutamate pyruvate transminase (sGPT), serum glutamate oxaloacetate transaminase (sGOT), alkaline phosphatase (sALP), Blood glucose level, Liver glycogen level and histopathological changes in liver were studied along with silimarin as standard Hepatoprotective agents. The Phytochemical investigation of the aqueous slurry showed significant decrease in the levels of sGPT, sGOT, sALP as compared to the animals treated with Silimarin, a known, standard hepatoprotective agent. A significant decrease in blood sugar level and liver glycogen was also observed in the animals treated with aqueous slurry of leaves of Salacia chinensis Linn.
Keywords	CCl4, Hepatoprotective, sGPT, sGOT, Salacia chinensis Linn.
Field	Biology
Published In	Volume 5, Issue 6, November-December 2023
Published On	2023-11-09
DOI	https://doi.org/10.36948/ijfmr.2023.v05i06.8567
Short DOI	https://doi.org/gs38g2

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