International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 6 Issue 5 September-October 2024 Submit your research before last 3 days of October to publish your research paper in the issue of September-October.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 6 Issue 5
September-October 2024

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

Potential of Trimetazidine in Protecting the Myocardium on Coronary Artery Bypass Grafting Surgery: A Systematic Review and Meta-Analysis

Author(s) Muhammad Sabri, Annisa Tria Fadilla, Hariadi Hatta, Brilliant, Moch Habib
Country Indonesia
Abstract Aims: Increased biochemicals such as Troponin T, CKMB, and CK from myocardial injury are side effects of CABG. Trimetazidine is an anti-ischemic agent that can also have a cardioprotective. We conducted a systematic review and meta-analysis to analyse the role of trimetazidine therapy on postoperative myocardial preservation in CABG. Methods: The research instrument used was RCT test articles that have been published in the PubMed, Cochrane, and Google Scholar databases in 2013 and 2023. We were classified into two group analyses based on sampling time (at least ≤12 or >12 hours after CABG). Results: Five RCTs were finally included in the meta-analysis. Significant differences in TnT, CK-MB, and CK were found between trimetazidine-treated CABG patients and control CABG patients (p < 00001) in the subgroup examinations conducted ≤12 and >12 post-CABG, indicating significantly lower postoperative TnT, CK-MB, and CK levels in trimetazidine-treated CABG patients compared with control CABG patients. Conclusion: Myocardial preservation of CABG by comparing the effects of trimetazidine and placebo by assessing several levels of myocardial damage such as TnT, CK-MB, and CK was significantly lower in CABG patients treated with trimetazidine compared with control CABG patients.
Keywords Trimetazidine, Protecting the Myocardium, CABG, Systematic Review and Meta-Analysis
Field Medical / Pharmacy
Published In Volume 5, Issue 6, November-December 2023
Published On 2023-11-20
Cite This Potential of Trimetazidine in Protecting the Myocardium on Coronary Artery Bypass Grafting Surgery: A Systematic Review and Meta-Analysis - Muhammad Sabri, Annisa Tria Fadilla, Hariadi Hatta, Brilliant, Moch Habib - IJFMR Volume 5, Issue 6, November-December 2023. DOI 10.36948/ijfmr.2023.v05i06.9145
DOI https://doi.org/10.36948/ijfmr.2023.v05i06.9145
Short DOI https://doi.org/gs5mfv
View / Download PDF File

Share this



E-ISSN 2582-2160
CrossRef

CrossRef DOI is assigned to each research paper published in our journal.

IJFMR DOI prefix is
10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form Cover Page Vol 6 Isu 5Cover Page Vol 6 Isu 4Cover Page Vol 6 Isu 3

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9898-5948-55 editor@ijfmr.com