International Journal For Multidisciplinary Research

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Frequency of Occurrence of Leukocytosis in Patients with Acute Exacerbation of Copd at a Tertiary Centre

Author(s) Pulkit Gupta, Smriti Khari, Saurabh Ojha, Anil Maurya, Ravi Kant Pandey
Country India
Abstract COPD is a major cause of chronic morbidity and mortality; it is currently the fourth highest cause of death in the world, and is predicted to be the third leading cause of mortality worldwide by the year 2020 [1-2]. COPD is identified mainly according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines; [post bronchodilator forced expiratory volume in 1 s (FEV1)/forced vital capacity ratio less than 0.7; severity determined by FEV1 alone] combined with a history of exposure to risk factors [2]. Exacerbations of respiratory symptoms in COPD are of major importance because of their profound and long lasting adverse effects on patients [3]. Frequent episodes accelerate loss of lung function, affect the quality of life of patients, and are associated with poor survival. There are some specific blood biomarkers for predicting lung function decline, acute exacerbation, or even mortality from big longitudinal cohort studies. However, their performance is depressing [4] . Peripheral blood leukocytosis has already been well investigated in the aspect of inflammatory biomarkers for COPD. The level of leukocytes is a key parameter in the clinical assessment of patients with COPD exacerbation, with and without fever. The presentation of high WBC count makes it important to distinguish the effect of the glucocorticosteroid from the effect of the possible infection [5-7].
Keywords Chronic obstructive pulmonary disease, exacerbation, inflammatory biomarker, leukocytosis, lung funtion.
Field Medical / Pharmacy
Published In Volume 5, Issue 6, November-December 2023
Published On 2023-12-03
Cite This Frequency of Occurrence of Leukocytosis in Patients with Acute Exacerbation of Copd at a Tertiary Centre - Pulkit Gupta, Smriti Khari, Saurabh Ojha, Anil Maurya, Ravi Kant Pandey - IJFMR Volume 5, Issue 6, November-December 2023. DOI 10.36948/ijfmr.2023.v05i06.9733
DOI https://doi.org/10.36948/ijfmr.2023.v05i06.9733
Short DOI https://doi.org/gs7v3b
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