International Journal For Multidisciplinary Research

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Invitro Antifungal Activity of Ziziphusmauritiana Extraction Against Clinical Isolates of Candida Spp at Khartoum State, 2021

Author(s) Twasol Ali Omer Hamed, MudathirAbdalshafiea, R M Elmagzoub, Mervet Mohammed Mazhar Abdelgadir, Mohammed Nafie Hammad
Country Sudan
Abstract experimental biomedical study was carried out at Omdurman Maternal Hospital, Saudi Maternal Hospital and AlzaiemAlazhari University during the period from September to December 2021. 30 Candida species, of them 17 isolated from urine samples and 13 from vaginal swabs were included in this study. Antifungal activity was performed usingcup plate method using different concentrations of plant extraction (100%, 50% and 25%) and fluconazole(10μg). The statistical analysis was performed using SPSS version 20. Results: the results showed significant increase in antifungal activity with increase in Ziziphusmauritianaconcentration, while fluconazole showed best antifungal activity.However, the fungicidal concentration showed that Ziziphusmauritiana methanol extracts was able to inhibit Candia SPPs rather than C. albicans.
Keywords Ziziphusmauritianaconcentration, fluconazole, Candida SPPs
Field Biology > Medical / Physiology
Published In Volume 5, Issue 6, November-December 2023
Published On 2023-12-04
Cite This Invitro Antifungal Activity of Ziziphusmauritiana Extraction Against Clinical Isolates of Candida Spp at Khartoum State, 2021 - Twasol Ali Omer Hamed, MudathirAbdalshafiea, R M Elmagzoub, Mervet Mohammed Mazhar Abdelgadir, Mohammed Nafie Hammad - IJFMR Volume 5, Issue 6, November-December 2023. DOI 10.36948/ijfmr.2023.v05i06.9917
DOI https://doi.org/10.36948/ijfmr.2023.v05i06.9917
Short DOI https://doi.org/gs7vzq
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