Prevalence Of Metabolic Syndrome In Vitiligo: A Cross-sectional Study

Manisha Koirala; Rushma Shrestha; Anupama Karki; Goma Dhami

doi:10.36948/ijfmr.2024.v06i05.29593

Prevalence Of Metabolic Syndrome In Vitiligo: A Cross-sectional Study

Author(s)	Manisha Koirala, Rushma Shrestha, Anupama Karki, Goma Dhami
Country	Nepal
Abstract	Introduction Vitiligo is a common acquired hypomelanotic disorder of the skin and is characterized by depigmented macules and patches that can appear anywhere on the skin. In pathogenesis, the researchers have suggested an interplay of multiple factors such as genetic, neural, oxidant-antioxidant, biochemical, minerals, and autoimmune processes in the induction of vitiligo. Metabolic syndrome (MetS), also known as Syndrome X is a pathological condition typically characterized by the combination of various interrelated metabolic disorders that include abdominal obesity, impaired glucose tolerance, dyslipidemia, and hypertension. The linkage of skin diseases and MetS is due to ongoing chronic inflammation due to elevated pro-inflammatory cytokines, imbalance between reactive oxygen species and antioxidants, and hormonal abnormalities mostly insulin resistance. Methodology This cross-sectional study included patients diagnosed with vitiligo and above 16 years of age. All the patients were sent for analysis of fasting lipid profile and fasting blood glucose level. The waist circumference was measured at the mid-point between the lower border of the rib cage and the iliac crest with a flexible inch tape. The blood pressure was taken in a sitting posture after 10 minutes of rest. The data was collected using a preformed proforma. Results Of the 70 patients, the majority (N=38) were male. The mean age was 37 years with a range from 16 to 79 years. The mean age of male patients was 39.87 ± 17.24 years and female patients was 33.59 ± 13.58 years. The most common clinical type of vitiligo was generalized vitiligo (48.6%) followed by focal (18.6%) and segmental (15.7%). The metabolic syndrome was present in 26 patients (37.1%). The patient with generalized vitiligo had maximum prevalence (n=10) followed by acrofacial vitiligo (n=6). Conclusion This study found a high prevalence of metabolic syndrome and its components in patients with vitiligo. Therefore, vitiligo patients need to be screened for metabolic syndrome to prevent unforeseen complications.
Keywords	Metabolic syndrome, Syndrome X, Vitiligo.
Field	Medical / Pharmacy
Published In	Volume 6, Issue 5, September-October 2024
Published On	2024-10-29
Cite This	Prevalence Of Metabolic Syndrome In Vitiligo: A Cross-sectional Study - Manisha Koirala, Rushma Shrestha, Anupama Karki, Goma Dhami - IJFMR Volume 6, Issue 5, September-October 2024. DOI 10.36948/ijfmr.2024.v06i05.29593
DOI	https://doi.org/10.36948/ijfmr.2024.v06i05.29593
Short DOI	https://doi.org/g8p2ts

View / Download PDF File

E-ISSN 2582-2160

doi

CrossRef DOI is assigned to each research paper published in our journal.

IJFMR DOI prefix is
10.36948/ijfmr

Downloads

Research Paper Format Copyright Permission Form and Undertaking Form Cover Page Vol 6 Isu 6 Cover Page Vol 6 Isu 5 Cover Page Vol 6 Isu 4

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA

About IJFMR Fees & Payment Current Issue Publication Archive	Submit Research Paper Track Submission Status Publication Guidelines Publication Ethics Peer Review & Plagiarism	Join as a Reviewer Editors & Reviewers Reviewer Referral Program Get Reviewer Membership Certi.	Website/Journal Policies Usage Policy Content Policies Privacy Policy

Contact Us		+91-9898-5948-55	editor@ijfmr.com

International Journal For Multidisciplinary Research

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Prevalence Of Metabolic Syndrome In Vitiligo: A Cross-sectional Study

Share this