International Journal For Multidisciplinary Research

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Ameliorative Role of Moringa Oleifera against Gamma Radiation and Mercury Induced Nephrotoxicity in Swiss Albino Mice

Author(s) Manisha Agarwal, Manoj Kumar, Archana Purohit, Aruna Chakrawarti, R.K. Purohit
Country India
Abstract Herbal plants and products represent important source of natural antioxidant and offer an alternative to synthetic protectors. Moringa oliefera, a herbal medicinal plant has been screen for their radioprotective activity. For the purpose of study male Swiss albino mice were divided into seven groups. The mice were exposed to gamma radiation (2.5 Gy and 5.0 Gy) and also provided mercuric chloride (0.5 ppm) both separately and combined. The herbal radioprotector Moringa was given to experimental groups after irradiation and mercury treatment. Animals were autopsied at post treatment interval of 1, 2, 4, 7, 14 and 28 days. After sacrificing the animal’s histopathology of kidney was observed. Renal glomeruli and tubules depicted degenerative changes and changes were more pronounced in combined treatment groups. Moringa treated groups demonstrated early and fast onset of recovery in comparison to non-Moringa treated groups. Radioprotective efficacy of MOE was due to presence of various bioactive compound.
Keywords Moringa, Radiation, Mercury, Kidney, Mice
Field Biology > Zoology
Published In Volume 4, Issue 5, September-October 2022
Published On 2022-09-18
Cite This Ameliorative Role of Moringa Oleifera against Gamma Radiation and Mercury Induced Nephrotoxicity in Swiss Albino Mice - Manisha Agarwal, Manoj Kumar, Archana Purohit, Aruna Chakrawarti, R.K. Purohit - IJFMR Volume 4, Issue 5, September-October 2022. DOI 10.36948/ijfmr.2022.v04i05.038
DOI https://doi.org/10.36948/ijfmr.2022.v04i05.038
Short DOI https://doi.org/10/gqvmzn
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